A little collection of commonly performed calculations for the estimation of renal function

**Formulae**
*Cockcroft-Gault*
A commonly used surrogate marker for estimation of creatinine clearance.

Equation: gfr = ((140-age)xweightxC)/creatinine C= 1.23 men, 1.04 women

*Modification of Diet in Renal Disease (MDRD)*
The commonly used formula is the "4-variable MDRD," which estimates GFR using four variables: serum creatinine, age, race, and gender

Equation: 32788 x creatinine^-1.154 x age^ -0.203 x 1.212 (if black) x .742 (if female)

This formula does not adjust for body mass, and tends to underestimate eGFR for heavy people and overestimate it for underweight people.

* CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)*
Developed in an effort to create a formula more accurate than the MDRD formula, especially when the actual GFR is greater than 60 mL/min per 1.73 m2. CKD-EPI may provide improved cardiovascular risk prediction over the MDRD Study formula in a middle-age population.

See:

Wikipedia on Renal function
**Disclaimer**
This applet is free for your personal use. However please note that use of this applet is for educational purposes only and you use the information provided here at your own risk. You are advised to double check the values obtained here prior to use.